Table 1.

Glossary of terms

Term	Definition/description
AUD	Alcohol Use Disorder
ChIP-Seq	Chromatin immunoprecipitation with sequencing
CNS	Central nervous system
DHSs	DNase I hypersensitive sites
DNase	Deoxyribonuclease
eQTL	Expression quantitative trait locus
GCTA	Genomewide Complex Trait Analysis (Yang et al. 2011)
GWAS	Genome-wide association study
H3K4me3	Trimethylation of lysine 4 on the histone H3 protein subunit regulatory mark
LD	Linkage disequilibrium
LDScR	Linkage Disequilibrium Score Regression (Bulik-Sullivan et al., 2015)
MAGMA	Multi-marker Analysis of GenoMic Annotation (de Leeuw et al. 2015)
meQTL	Methylation quantitative trait locus
mRNA	Messenger RNA
NetWAS	Network-wide association study
PLINK	Statistical genetics software program (Purcell et al. 2007; Chang et al. 2015)
PPI	Protein-protein interaction
RNA-Seq	RNA sequencing
SNP	Single-nucleotide polymorphism
TWAS	Transcriptome-wide association studies (Gusev et al. 2016)
VEGAS	Versatile gene-based association study (Liu et al. 2010; Mishra et al. 2015)