Fig. 3.

Enoxacin-Induced Lifespan Extension Is Mediated by the miRNA Pathway. (a,b,c) Lifespan of (a) dcr-1(ok247), (b) alg-1(gk214) and (c) rde-4(ne301) mutants treated with enoxacin. Data was compared using the log-rank test and statistics is available in Table S3. Graphics represent a compilation of at least 2 independent experiments. (d) Heatmap representing hierarchical clustering of miRNAs with at least 2-fold regulation when comparing adult wild type worms treated with enoxacin vs. vehicle.