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. 2018 Jul 9;8:10358. doi: 10.1038/s41598-018-28563-y

Table 1.

Summary of the 1,650 study participants: classified into normal liver and fatty liver groups of FL, NAFL and AFL.

NL FL NAFL AFL
Number of subjects in group 1,334 316 223 55
Age, years 41.55 (5.07) 43.16 (4.73) 42.91 (4.83) 44.47 (4.32)
Males (%) 534 (40.0) 221 (69.9) 151 (67.7) 42 (76.4)
Body mass index, kg/m2 25.60 (4.37) 30.75 (5.43) 30.99 (5.64) 30.01 (5.17)
Waist to hip ratio 0.88 (0.08) 0.98 (0.07) 0.98 (0.08) 0.99 (0.08)
Daily smokers (%) 172 (13.5) 48 (16.6) 34 (15.3) 14 (25.5)
Diabetics (%) 22 (1.7) 41 (13.1) 28 (12.7) 8 (14.5)
Metabolic syndrome (%) 167 (12.7) 183 (59.0) 130 (59.4) 33 (62.3)
Systolic BP, mmHg 117.38 (13.60) 128.22 (14.20) 126.89 (13.09) 132.61 (14.82)
Diastolic BP, mmHg 73.56 (9.86) 82.38 (10.64) 82.01 (10.61) 83.40 (10.89)
Apolipoprotein B, g/L 1.01 (0.26) 1.23 (0.33) 1.23 (0.33) 1.24 (0.31)
Triglycerides, mmol/L 1.15 (0.71) 2.04 (1.60) 2.07 (1.73) 1.96 (1.05)
Insulin, mU/L 8.11 (9.81) 17.70 (20.52) 17.81 (16.78) 14.69 (10.47)
ALT, U/L 14.40 (7.89) 26.91 (13.60) 26.57 (13.79) 30.16 (13.94)
AST, U/L 20.57 (5.43) 25.86 (6.99) 25.31 (6.99) 29.35 (7.03)
GT, U/L 24.90 (15.88) 46.66 (23.90) 45.29 (22.95) 58.03 (24.77)
CRP, mg/L 1.39 (2.14) 2.53 (3.24) 2.45 (3.09) 2.81 (3.78)
Alcohol consumption, drinks/day 0.71 (1.01) 1.25 (1.59) 0.65 (0.63) 3.70 (1.95)
Alcohol consumption, g/day 8.50 (12.16) 15.02 (19.13) 7.78 (7.53) 44.38 (23.42)
Physical activity index 9.20 (1.83) 8.40 (1.87) 8.50 (1.84) 8.06 (1.99)

Values are mean (SD).

Note: Alcohol consumption was available from 1,536 subjects. Statistics: Mann-Whitney test was used for continuous parameters and χ2 test for classified parameters when each fatty liver group was compared to controls (NL group). P < 0.001 for all other comparisons, except smoking (FL p = 0.209, NAFL p = 0.548 and AFL p = 0.022) and alcohol consumption (NAFL p = 0.192).

Abbreviations: NL, normal liver; FL, Fatty liver; NAFL, non-alcoholic fatty liver; AFL, alcoholic fatty liver; ALT, alanine aminotransferase; AST, aspartate aminotransferase; GT, glutamyltransferase; CRP, C-reactive protein.