Table 1.
Effect of FR on hemodynamic and urine and plasma parameters.
| CT | FR | P value (<) | |
|---|---|---|---|
| Mean ± SEM, N | Mean ± SEM, N | ||
| MAP (mmHg) | 113 ± 1.9, n = 33 | 107 ± 1.6, n = 32 | 0.03 ‡ |
| HR (bpm) | 380 ± 5.8, n = 33 | 357 ± 8.9, n = 32 | 0.03 ‡ |
| Plasma Aldosterone (pg/mL) | 783 ± 123, n = 8 | 1020 ± 155, n = 7 | 0.2 |
| Hematocrit (fraction) | 0.45 ± 0.002, n = 7 | 0.48 ± 0.007, n = 6 | 0.001 ‡ |
| Plasma volume (mL) | 9.0 ± 1.0, n = 8 | 6.1 ± 0.7, n = 8 | 0.03 ‡ |
| Urine volume (mL/24 h) | 11.6 ± 0.7, n = 8 | 5.0 ± 0.3, n = 8 | 0.001 ‡ |
| Na+ intake (mmol/24 h) | 1.893 ± 0.087, n = 8 | 0.673 ± 0.002, n = 8 | 0.001 ‡ |
| UNa (mmol/L) | 165.7 ± 4.7, n = 8 | 141.6 ± 11.7, n = 8 | 0.09 |
| UNaV (mmol/24 h) | 1.92 ± 0.10, n = 8 | 0.70 ± 0.045, n = 8 | 0.001 ‡ |
| Na+ intake - UNaV (mmol/24 h) | −0.05 ± 0.05, n = 8 | −0.05 ± 0.05, n = 8 | 0.99 |
| Plasma Na+ concentration (mmol/L) | 138.7 ± 0.9, n = 8 | 142.3 ± 1.4, n = 8 | 0.056 |
| K+ intake (mmol/24 h) | 4.033 ± 0.18549, n = 8 | 1.430 ± 0.0051, n = 8 | 0.001 ‡ |
| UK (mmol/24 h) | 361 ± 1130, n = 8 | 321 ± 1232, n = 8 | 0.04 ‡ |
| UKV (mmol/24 h) | 4.15 ± 0.164, n = 8 | 1.59 ± 0.051, n = 8 | 0.001 ‡ |
| K+ intake - UKV (mmol/24 h) | −0.19 ± 0.113, n = 8 | −0.22 ± 0.051, n = 8 | 0.8 |
| Plasma K+ concentration (mmol/L) | 5.3 ± 0.26, n = 8 | 4.9 ± 0.13, n = 8 | 0.3 |
| Urine protein (mg/mL) | 10.7 ± 0.41, n = 8 | 11.8 ± 0.71, n = 7 | 0.2 |
Basal physiological values in female rats subjected to control (CT) or food restricted (FR) diet for 14 days. ‡P < 0.05 vs CT, by unpaired Student’s t-test. BW, body weight; MAP, mean arterial pressure; HR, heart rate; UNaV, urinary excretion of Na+; UKV, urinary excretion of K+.