Table 2.

Demographics of patients with cancer divided by tertiles of D-dimer values between days 7 and 28.

	1st tertile DD < 3.0 (n = 7)	2nd tertile DD 3.0–9.0 (n = 6)	3rd tertile DD ≥ 9.1 (n = 8)	p-value
Age, years (mean ± SE)	78.6 ± 3.56	72.8 ± 3.91	75.1 ± 3.47	n.s.
Male sex, n (%)	3 (43%)	4 (57%)	6 (75%)	n.s.
NIHSS	3.14 ± 0.77	4.83 ± 7.74	4.13 ± 0.91	n.s.
Body mass index (mean ± SE)	17.7 ± 0.83	22.3 ± 1.84	20.4 ± 1.31	n.s.
Advanced stage of cancer	5 (71%)	6 (100%)	8 (100%)	n.s.
Died within 500 days	3 (43%)	6 (100%)	8 (100%)	<0.005
within 90 days	2 (29%)	1 (17%)	7 (88%)	<0.01
Risk factors
Hypertension	3 (43%)	3 (50%)	3 (38%)	n.s.
Diabetes	0 (0%)	4 (67%)	1 (13%)	n.s.
Hyperlipidemia	1 (14%)	3 (50%)	2 (25%)	n.s.
Smoking	2 (29%)	1 (17%)	3 (38%)	n.s.
Preventive therapy for infarction
Anticoagulant therapy	0 (0%)	0 (0%)	1 (13%)	n.s.
Antiplatelet therapy	0 (0%)	3 (50%)	1 (13%)	n.s.
Anticoagulant therapy after stroke	6 (86%)	4 (67%)	7 (88%)	n.s.
Maximum size of lesion < 15 mm	3 (43%)	2 (33%)	4 (40%)	n.s.
Infarcts on multiple vascular territories	5 (71%)	5 (83%)	6 (75%)	n.s.
D-dimer value (μg/mL)
On admission	5.27 ± 1.84	6.87 ± 1.22	25.04 ± 4.91	<0.001
During days 7–28	1.77 ± 0.35	4.52 ± 0.65	24.45 ± 4.05	<0.0001
Recurrence of stroke	1 (14%)	2 (33%)	2 (25%)	n.s.

SE, standard error; n.s., not significant.