Table 2.
DLB/ADC+ | DLB/AD− | AD | |
---|---|---|---|
(n = 41) | (n = 41) | (n = 41) | |
Age, years | 71 (6.6) | 69 (6.3) | 69 (7.1) |
Symptom duration, years | 2.6 (1.8) | 3.6 (2.6) | 3.4 (2.3) |
Sex, male (%) | 31 (76) | 37 (90) | 36 (88) |
Hallucinations (%) | 18 (44) | 11 (27) | 2 (7)ab |
Extrapyramidal signs (%) | 17 (50) | 30 (77)c | 1 (3)ab |
n = 34 | n = 39 | n = 37 | |
Medication | 12 (30) | 9 (22) | 7 (17) |
cholinesterase inhibitor | 3 (7) | 3 (7) | 6 (14) |
benzodiazepine | 8 (20) | 3 (7) | 1 (2)a |
antidepressant | 5 (12) | 1 (2) | 0 |
antipsychotic | 2 (5) | 2 (5) | 0 |
MMSE | 20 (5.6) | 24 (3.6)c | 22 (5.1) |
n = 40 | n = 39 | ||
CSF AB42 pg/ml | 501 (136) | 811 (263)c | 461 (134)b |
median (IQR) | 479 (215) | 774 (385) | 461 (159) |
CSF total TAU, pg/ml | 540 (260) | 242 (79)c | 640 (335)b |
median (IQR) | 496 (319) | 245 (94) | 570 (262) |
CSF pTAU, pg/ml | 73 (32) | 41 (13)c | 91 (39)b |
median (IQR) | 65 (35) | 42 (13) | 82 (43) |
123I[FP-CIT]-scan available | 11 (27%) | 17 (41%) |
Data are mean (SD) or n(%) unless otherwise specified. MMSE = mini mental state examination, CDR = clinical dementia rate, CSF = cerebrospinal fluid. ap < 0.05 DLB/AD+ vs. AD, bp < 0.05 DLB/AD− vs. AD, cp < 0.05 DLB/AD+ vs. DLB/AD−.