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. 2018 Jul 3;9:1367. doi: 10.3389/fmicb.2018.01367

Figure 7.

Figure 7

TB pipeline: molecules in phase I clinical trials. Source: https://www.newtbdrugs.org/pipeline/clinical. For each molecule physicochemical characteristics are reported, along with the violation to the “rule of five.” Physicochemical properties calculated at http://www.molinspiration.com/cgi-bin/properties. *Structure not released.