Figure 6.
NGF expression in normal and ulcerated mucosa of young and aging rats. Immunostaining for NGF in gastric mucosa of young (A and D) and aging (B and E) rats. Quantitative analysis of NGF immunostaining showed reduced NGF expression in ECs of mucosal (C) and submucosal (F) vessels in both normal and ulcerated gastric mucosa of aging rats compared to young rats. Scale bars: 20 μm. *P < .05; **P < .005. Student's t-test and one-way analysis of variance with Tukey's multiple comparison tests were used to determine statistical significance between 2 or multiple groups, respectively.