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. 2018 Jun 22;18:77–83. doi: 10.1016/j.redox.2018.06.007

Fig. 1.

Fig. 1

Expression of NRF2 declines in old endothelial cells. A) qPCR measurement for NRF2-expressing gene, Nuclear Factor, Erythroid 2 Like 2 (NFE2L2) (n = 3) and a representative Western blot for NRF2 in young (p4) and old (p16) HUVECs. B) Expression of NRF2 target gene, HMOX1, in young (p4) and old (p16) HUVECs. C) Expression of NFE2L2 and HMOX1 mRNA (n = 6) in oxPAPC-treated (30 µg/ml, 10 h) cells. Fold changes for the indicated cell passages are calculated against respective control values. (For all: mean±SD, *p < 0.05, **p < 0.01, ***p < 0.001).