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. Author manuscript; available in PMC: 2018 Jul 10.
Published in final edited form as: Nature. 2018 Apr 18;556(7702):501–504. doi: 10.1038/s41586-018-0052-z

Extended Data Fig. 7. DI shows a lack of in vivo toxicity.

Extended Data Fig. 7

a, Schematic of DI administration for the analysis of succinate dehydrogenase (SDH) activity in the heart and the liver. b, SDH activity in the heart and the liver of mice treated as in a. Mean of n = 2 technical replicates. Representative data from two mice. c, Western blot of SDH and GAPDH in mitochondrial and cytoplasmic fractions from the heart and the liver of mice treated as in a. Representative of two mice. For gel source data, see Supplementary Fig. 1.