Table S12. Chromosomal instability.
| Factor | nBP ratio | LCI | UCI | uP value | mP value |
|---|---|---|---|---|---|
| Trial | |||||
| CALGB | 1.0 | 0.001 | <0.001 | ||
| IALT | 1.0 | 0.89 | 1.2 | ||
| JBR 10 | 1.3 | 1.1 | 1.5 | ||
| Age | |||||
| ≤55 | 0.96 | 0.86 | 1.1 | 0.631 | 0.327 |
| 55–64 | 1.0 | ||||
| ≥65 | 1.0 | 0.93 | 1.2 | ||
| Arm | |||||
| Control | 1.00 | 0.512 | 0.999 | ||
| Chemotherapy | 1.00 | 0.92 | 1.1 | ||
| Sex | |||||
| Woman | 1.0 | 0.013 | 0.009 | ||
| Men | 1.1 | 0.99 | 1.2 | ||
| PS | |||||
| 0 | 1.0 | 0.002 | 0.047 | ||
| 1–2 | 1.1 | 0.99 | 1.2 | ||
| Surgery | |||||
| Lobectomy/other | 1.0 | 0.016 | 0.163 | ||
| Pneumonectomy | 1.0 | 0.94 | 1.2 | ||
| Histology | |||||
| Adenocarcinoma | 1.0 | <0.001 | 0.194 | ||
| Squamous cell carcinoma | 1.1 | 0.99 | 1.2 | ||
| Other | 1.1 | 0.93 | 1.2 | ||
| T stage | |||||
| T1 | 1.1 | 0.93 | 1.2 | 0.117 | 0.470 |
| T2 | 1.0 | ||||
| T3/T4 | 1.1 | 0.92 | 1.2 | ||
| N stage | |||||
| N0 | 0.99 | 0.89 | 1.1 | 0.050 | 0.775 |
| N1 | 1.0 | ||||
| N2 | 1.0 | 0.90 | 1.2 |
nBP ratio, the ratio between the expected number of breakpoints (BPs) as compared to the reference class; LCI and UCI, lower and upper bounds of the 95% confidence interval; uP value, P value in the univariate analyses (Kruskal-Wallis test); mP value, P value in the multivariate analysis (likelihood ratio test).