Table 1.
Controls | L-NAME | L-NAME + Los | ||||
---|---|---|---|---|---|---|
|
|
|
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Baseline week 2 (n = 6) | Baseline week 2 (n = 6) | Baseline week 2 (n = 6) | ||||
Body weight g | 233.00 ± 12.04 | 296.00 ± 11.40 | 233.00 ± 12.04 | 309.20 ± 16.76 | 233.00 ± 12.04 | 296.00 ± 11.40 |
Uric acid mg/dl | 0.60 ± 0.12 | 0.62 ± 0.10 | 0.82 ± 0.45 | 1.82 ± 0.23* | 0.60 ± 0.14 | 0.60 ± 0.07 |
Creatinine mg/dl | 0.48 ± 0.20 | 0.34 ± 0.05 | 0.34 ± 0.05 | 0.42 ± 0.08 | 0.36 ± 0.08 | 0.38 ± 0.04 |
Proteinuria mg/24 h | 3.46 ± 1.66 | 2.83 ± 2.03 | 3.65 ± 0.85 | 7.45 ± 1.46*** | 2.72 ± 1.47 | 3.20 ± 1.17 |
SBP mm Hg | 115.44 ± 4.16 | 117 ± 2.88 | 115.44 ± 4.16 | 197.86 ± 17.06*** | 115.44 ± 4.16 | 125 ± 6.85 |
Values are shown as means ± SD. n = 6.
p < 0.05 versus Control and L-NAME + Los groups.
p < 0.001 versus Control and L-NAME + Los groups.