Table 4.
Correlation of citrate synthase (anti‐CS) IgG and immunoglobulin (Ig)M antibody levels with antibacterial antibody titres in plasma and PF of patients with cardiovascular diseases
| Disease group | CABG no MI | CABG with MI | AVR |
|---|---|---|---|
| Natural autoantibody | Correlating anti‐microbial antibody | ||
| Anti‐CS IgG plasma | MP IgG (plasma) (rho = 0·789; P = 0·004) | CP IgG (plasma) (rho = 0·753; P = 0·012) | No correlation |
| MP IgM (plasma) (rho = 0·802; P = 0·003) | CP IgG (PF) (rho = 0·769; P = 0·026) | ||
| MP IgG (PF) (rho = 0·579; P = 0·062) | BB IgG (plasma) (rho = 0·632; P = 0·049) | ||
| Anti‐CS IgG PF | MP IgG (plasma) (rho = 0·797; P = 0·003) | CP IgG (plasma) (rho = 0·754; P = 0·012) | No correlation |
| MP IgM (plasma) (rho = 0·829; P = 0·002) | CP IgG (PF) (rho = 0·762; P = 0·028) | ||
| MP IgG (PF) (rho = 0·611; P = 0·046) | BB IgG (plasma) (rho = 0·633; P = 0·049) | ||
| Anti‐CS IgM plasma | No correlation | YE IgM (plasma) (rho = 0·710; P = 0·021) | MP IgG (plasma) (rho = 0·780; P = 0·013) |
| Anti‐CS IgM PF | No correlation | No correlation | No correlation |
Aortic valve replacement group (AVR, n = 10), coronary artery bypass grafting patients (CABG) with previous myocardial infarction (CABG with MI, n = 10), and those who underwent CABG but had no previous myocardial infarction (CABG no MI, n = 12). MP = Mycoplasma pneumoniae; CP = Chlamydia pneumoniae; BB = Borrelia burgdorferi; YE = Yersinia enterocolitica.