Table 4.
Cannabis sativa F7, F3, and F7+F3 Cytotoxic Activity on Human Colon Polyp and Healthy Colon Tissue
| % Living cells | |||||
|---|---|---|---|---|---|
| Sample | P1 | P2 | P3 | P4 | |
| Healthy tissue | NT | 100A | 100A | 100A | 100B |
| F3 | 68.5B | 51.3B | 18.1B | 122.5A | |
| F7 | 54.4C | 25.2C | 4.9C | 97.3C | |
| F3+F7 | 55.4BC | 30.0C | 7.6C | 16.3D | |
| Polyp | NT | 100a | 100a | 100a | 100c |
| F3 | 24.4b | 77.2b | 13.0c | 119.7b | |
| F7 | 15.4c | 63.4bc | 5.8d | 142.1a | |
| F3+F7 | 16.1c | 51.7c | 33.5b | 40.6d | |
Cytotoxic activity was calculated as % of living cells from control of tissue treated with methanol only (NT+MeOH). Healthy biopsy of normal tissue (n=4); Polyp biopsy of adenomatous polyp (n=4). Percentages with different letters are significantly different from all combinations of pairs by Tukey HSD.
HSD, honest significant difference.