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PKM2 is directly regulated by miR-148a and miR-326 in TC. A. Predicted putative miR-148a and miR-326-binding sites in the 3’-untranslated region (UTR) of PKM2. B. The mRNA and protein expression of PKM2 after miR-148a or miR-326 overexpression in TPC-1 and K1 cells. C. miR-148a or miR-326 suppressed the relative luciferase activity in constructs that contained the 3’-UTR of PKM2.
