Effects of intrastriatal injection of Lv-Nurr1-MSCs on the morphology of the CD11b-, GFAP-, COX-2- and TNF-α-positive cells and the integrated absorbance (IA) of CD11b, GFAP, COX-2 and TNF-α in mRNA level of the substantia nigra. CD11b-positive cells (A1-A4); GFAP-positive cells (B1-B4); COX-2-positive cells (C1-C4); TNF-α-positive cells (D1-D4); Representative RT-PCR of CD11b, GFAP, COX-2 and TNF-α in the SN. GAPDH was used as an internal control (E). The relative mRNA level of CD11b, GFAP, COX-2 and TNF-α was analyzed by RT-PCR (Δ
P<0.01, ΔΔ
P<0.05) (F). 1: normal side of the saline group; 2: saline-injected side of the saline group; 3: Lv-MSCs-injected side of the Lv-MSCs group; 4: Lv-Nurr1-MSCs-injected side of the Lv-Nurr1-MSCs group. The number of rats in each group was five. Scale bar = 20 μm.