Table 3.
Top 20 down-regulated proteins in iTRAQ
| Accession No. | Protein name | Gene name | iTRAQ ratio (pORF5-HeLa:vector-HeLa) |
|---|---|---|---|
| K1C17_HUMAN | Keratin, type I cytoskeletal 17 | KRT17 | 0.26142584 |
| S10AA_HUMAN | Protein S100-A10 | S100A10 | 0.271784767 |
| S10A6_HUMAN | Protein S100-A6 | S100A6 | 0.274299862 |
| CALM_HUMAN | Calmodulin | CALM1 | 0.340538161 |
| MLRS_HUMAN | Myosin regulatory light chain 2, skeletal muscle isoform | MYLPF | 0.365365015 |
| ENSA_HUMAN | Alpha-endosulfine; ARPP-19e | ENSA | 0.38758936 |
| ANXA2_HUMAN | Annexin A2 | ANXA2 | 0.387849079 |
| PEPL_HUMAN | Periplakin | PPL | 0.410372104 |
| LMO7_HUMAN | LIM domain only protein 7 | LMO7 | 0.416502052 |
| 1433F_HUMAN | 14-3-3 protein eta | YWHAH | 0.430896453 |
| 1433S_HUMAN | 14-3-3 protein sigma | SFN | 0.439577358 |
| CAPG_HUMAN | Macrophage-capping protein | CAPG | 0.442593018 |
| ZO2_HUMAN | Tight junction protein ZO-2 | TJP2 | 0.467977633 |
| K2C1_HUMAN | Keratin, type II cytoskeletal 1 | KRT1 | 0.478392317 |
| K2C7_HUMAN | Keratin, type II cytoskeletal 7 | KRT7 | 0.48338675 |
| EPS15_HUMAN | Epidermal growth factor receptor substrate 15 | EPS15 | 0.492188542 |
| AHNK2_HUMAN | Protein AHNAK2 | AHNAK2 | 0.503548636 |
| PGAM5_HUMAN | Serine/threonine-protein phosphatase PGAM5, mitochondrial | PGAM5 | 0.505856874 |
| OTUD5_HUMAN | OTU domain-containing protein 5 | OTUD5 | 0.511643101 |
| CNOT7_HUMAN | CCR4-NOT transcription complex subunit 7 | CNOT7 | 0.516671366 |