Table 3.
Levels of MDA and SOD in human blood samples after exposure to different Ozone concentrations
| Concentrations | 0 μg/mL | 40 μg/mL | 80 μg/mL | 160 μg/mL | P value |
|---|---|---|---|---|---|
| MDA (nmol/mg prot-1) | |||||
| AD group | 7.53 (6.68-8.11) | 7.10 (6.09-8.02) | 7.36 (6.38-7.96) | 9.37 (8.51-10.01)a,b,c | <0.001 |
| Control group | 6.71 (5.13-7.87) | 6.46 (5.42-7.46) | 6.08 (5.39-7.45) | 8.93 (8.23-9.55)a,b,c | <0.001 |
| P value | 0.028 | 0.152 | 0.012 | 0.310 | |
| SOD (U/mg prot-1) | |||||
| AD group | 12.50 (11.83-13.33) | 14.45 (13.45-15.71)a | 15.33 (13.71-16.36)a | 10.85 (10.25-11.96)b,c | <0.001 |
| Control group | 13.10 (12.48-14.35) | 16.38 (15.38-17.67)a | 16.88 (15.88-18.49)a | 12.13 (10.67-12.67)b,c | <0.001 |
| P value | 03e.110 | 0.006 | 0.012 | 0.055 |
Data was presented as median (25th-75th). Comparison among different concentrations was determined by Kruskal-Wallis H rank sum test, and a Dunn-Bonferroni test for post hoc comparisons. Comparison between AD group and C group was determined by Wilcoxon rank sum test. P<0.05 was considered significant.
a
Ozone concentrations 0 μg/mL vs 40 μg/mL, 80 μg/mL or 160 μg/mL are significantly different (P<0.05);
b
Ozone concentrations 40 μg/mL vs 80 μg/mL or 160 μg/mL are significantly different (P<0.05);
c
Ozone concentrations 80 μg/mL vs 160 μg/mL are significantly different (P<0.05).
AD, aortic dissection; MDA, malondialdehyde; SOD, superoxide dismutase.