Table 1.
Grade 0 | Grade 1 | Grade 2 | Grade 3 | |
---|---|---|---|---|
Fibronectin (cytoplasm) | Negative | Weak, focal | Weak, diffuse | Strong, diffuse |
CX43 (cytoplasm) | Negative | Scattered positivity | Patchy positivity | Diffuse positivity |
CX43 (ID and along LCB) | Negative | Thin linear and intermittent positivity | Dense but intermittent positivity | Dense band-like positivity |
NPCX43 (cytoplasm) | Negative | Scattered positivity | Patchy positivity | Diffuse positivity |
CX43 (ID and along LCB) | Negative | Thin linear and intermittent positivity | Dense but intermittent positivity | Dense band-like positivity |
ZO1 (cytoplasm) | Negative | Weak and patchy | Dense but patchy positivity | Diffuse positivity |
ID, intercalated discs; LCB, longitudinal cell membrane.