Table 1.
Clinicopathological characteristics of 502 patients with upper tract urothelial carcinoma
| All patients (n=502) | URS or not | |||
|---|---|---|---|---|
| Yes (n=206) | No (n=296) | p value | ||
| No. (%) | No. (%) | No. (%) | ||
| Age(years)(mean [SD]) | 65.8 (11.0) | 66.1 (10.1) | 65.7 (11.6) | 0.705 |
| Gender | 0.334 | |||
| Male (%) | 220 (43.8) | 85 (41.3) | 135 (45.6) | |
| Female (%) | 282 (56.2) | 121 (58.7) | 161 (54.4) | |
| Smoking | 0.984 | |||
| Yes (%) | 105 (20.9) | 43 (20.9) | 62 (20.9) | |
| No (%) | 397 (79.1) | 163 (79.1) | 234 (79.1) | |
| Bladder cancer history | 0.958 | |||
| Yes (%) | 148 (29.5) | 61 (29.6) | 87 (29.4) | |
| No (%) | 354 (70.5) | 145 (70.4) | 209 (70.6) | |
| eGFR (mL/min/1.73 m2) (median [range]) | 49.4 (2.9-154.3) | 0.544 | ||
| ≧ 60 (%) | 175 (34.9) | 75 (36.4) | 100 (33.8) | |
| <60 (%) | 327 (65.1) | 131 (63.6) | 196 (66.2) | |
| Dialysis | 0.476 | |||
| Yes (%) | 76 (15.1) | 34 (16.5) | 42 (14.2) | |
| No (%) | 426 (84.9) | 172 (83.5) | 254 (85.8) | |
| Surgical modality | *< 0.001 | |||
| Open (%) | 329 (65.5) | 110 (53.4) | 219 (74.0) | |
| Laparoscopy (%) | 155 (30.9) | 90 (43.7) | 65 (22.0) | |
| Segmental resection (%) | 18 (3.6) | 6 (2.9) | 12 (4.1) | |
| Tumor location | 0.711 | |||
| Pelvis (%) | 190 (37.8) | 76 (36.9) | 114 (38.5) | |
| Ureter (%) | 221 (44.0) | 95 (46.1) | 126 (42.6) | |
| Both (%) | 91 (18.1) | 35(17.0) | 56 (18.9) | |
| Multifocality | 0.389 | |||
| Yes (%) | 117 (23.3) | 44 (21.4) | 73 (24.7) | |
| No (%) | 385 (76.7) | 162 (78.6) | 223 (75.3) | |
| Tumor grade | 0.592 | |||
| Low (%) | 111 (22.1) | 48 (23.2) | 63 (21.3) | |
| High (%) | 391 (77.9) | 158 (76.7) | 233 (78.7) | |
| Pathologic T stage | 0.319 | |||
| pTa-Tis (%) | 71 (14.1) | 36 (17.5) | 35 (11.8) | |
| pT1 (%) | 131 (26.1) | 54 (26.2) | 77 (26.0) | |
| pT2 (%) | 127 (25.3) | 47 (22.8) | 80 (27.0) | |
| pT3 (%) | 144 (28.7) | 55 (26.7) | 89 (30.1) | |
| pT4 (%) | 29 (5.8) | 14 (6.8) | 15 (5.1) | |
| Pathologic N | 0.999 | |||
| N0 or Nx (%) | 463 (92.2) | 190 (92.2) | 273 (92.2) | |
| N1-3 (%) | 39 (7.8) | 16 (7.8) | 23 (7.8) | |
*p<0.05