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. 2018 Jul 9;37:141. doi: 10.1186/s13046-018-0824-1

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© The Author(s). 2018

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 1 — Cortactin was upregulated in lung cancer tissues and could be a marker of poorer prognosis in human NSCLC. a Expression profiles of CTTN in primary lung cancer and matched normal tissues were reported as 2^-∆Ct values. b and c Kaplan-Meier curves for progression-free survival (PFS) and overall survival (OS) according to expression levels of cortactin. PFS and OS rate were calculated by log-rank test. d Cortactin expression in lung cancer tissues was quantified as 2-^∆Ct values. Cortactin expression levels in primary metastasis-positive NSCLC tissues were compared with metastasis-negative tissues