Table 1.

Inclusion and Exclusion Criteria

Inclusion criteria:

Infants born at BWH and admitted to the Well Newborn Nursery, or to the BCH or BWH ICU

At least one biological parent to have genetic counseling, donate DNA, and provide consent for testing the infant

Exclusion criteria:

Parents are non-English speaking

Parents unwilling to have genomic reports placed in the medical record or sent to their primary care pediatrician

Mother or father younger than 18 years of age

Mother or father with impaired decisional capacity

Age of infant is older than 42 days

One of a multiple gestation

Any infant in which clinical considerations preclude drawing 1.0 ml of blood

Clinical exome ordered before the time of enrollment

Missing consent of either biological parent (if known) or rearing parent (if applicable)