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. 2018 Jul 9;20:69. doi: 10.1186/s13058-018-1002-2

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© The Author(s). 2018

Open Access This article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 7 — Examples of multi-modal spectral histopathology (MSH) measurements of whole breast conserving surgery (BCS) specimens for which histopathological examination identified negative margins. a-d MSH detected no tumor on the surface of 80% of specimens declared clear by histopathological examination. Distances from the measured margin to tumor are marked with green arrows. e MSH detected tumor although only lactation adenoma (LA) was found within 100 μm of the measured surface in sections sampled by histopathological examination