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. 2018 Jun 8;74(Pt 7):606–620. doi: 10.1107/S2059798318005612

Table 1. Summary of MR results by MR-REX and Phaser on 38 test proteins with decoy models generated by 3DRobot and LOMETS .

For each protein multiple decoy models are attempted, where the decoy with the lowest TM-score (for the 3DRobot decoys) or with the lowest sequence identity (for the LOMETS templates) which is successfully placed with a cRMSD of <2 Å is reported in the last four columns. The data in parentheses are obtained when a successful case is defined based on phenix.autobuild, i.e. an R free of <0.4 and the model quality is improved. M and CC in the fold class column indicate membrane and coiled coil, respectively.

            Worst TM-score Worst sequence identity (%)
Protein PDB code Length (amino acids) Resolution (Å) Solvent content Fold class Space group Phaser MR-REX Phaser MR-REX
1d2n 246 1.75 52 α/β P6 0.83 (0.83) 0.82 (0.86) 70 (70) 27 (70)
1okc 292 2.20 55 M P21212 0.76 (0.89) 0.76 (0.90) 52 (52) 52 (52)
1r0u 142 1.75 55 β P3221 0.84 (0.84) 0.84 (0.84) 100 (100) 100 (100)
1su0 136 2.30 42 α+β I422 0.79 (0.87) 0.76 (0.83) 22 (22) 22 (46)
1v05 96 1.43 35 β P6122 0.77 (0.77) 0.77 (0.83) 31 (31) 31 (31)
1vpq 260 2.20 44 α/β C2221 0.82 (0.87) 0.80 (0.91) 33 (100) 33 (33)
1x8y 74 2.20 71 CC P6522 0.81 (0.59) 0.77 (0.59) 64 (64) 64 (64)
2bou 137 1.90 61 β P21212 0.76 (0.86) 0.87 (0.87) 99 (99) 99 (99)
2il5 162 2.30 61 α+β P62 0.74 (0.85) 0.67 (0.85) 12 (17) 12 (17)
2p17 249 1.52 32 β P212121 0.77 (0.88) 0.79 (0.88) 35 (35) 35 (35)
2rbk 261 1.00 46 α/β P212121 0.79 (0.91) 0.90 (0.90) 21 (30) 30 (100)
2yq9 213 1.90 43 α/β P212121 0.74 (0.84) 0.77 (0.82) 48 (79) 48 (79)
3b7c 121 1.70 56 α+β P6522 0.83 (0.84) 0.75 (0.83) 15 (15) 15 (15)
3bw6 137 2.50 66 α/β P3221 0.79 (0.79) 0.72 (0.72) 40 (40) 40 (40)
3chv 279 1.45 40 α/β C121 0.74 (0.86) 0.77 (0.93) 61 (97) 24 (14)
3fzx 212 2.20 59 β P6422 0.83 (0.83) 0.81 (0.87) 41 (41) 41 (40)
3hyn 186 1.20 34 α/β P212121 0.86 (0.88) 0.81 (0.83) 96 (96) 96 (96)
3k93 223 2.15 60 α/β P321 0.74 (0.79) 0.74 (0.81) 98 (98) 98 (98)
3mt0 281 1.58 40 α/β P1211 0.81 (0.81) 0.84 (0.84) 30 (44) 44 (44)
3n2q 282 2.55 55 α/β P3121 0.85 (0.91) 0.86 (0.91) 40 (40) 40 (40)
3onj 97 1.92 35 α P212121 0.80 (0.83) 0.74 (0.88) 100 (100) 100 (100)
3pu6 138 2.60 44 α/β P212121 0.76 (0.88) 0.68 (0.84) 98 (98) 98 (98)
3pyw 178 1.80 65 α P41212 0.70 (0.70) 0.72 (0.72) 100 (100) 100 (100)
3q6b 155 1.50 39 α/β C121 0.62 (0.59) 0.62 (0.59) 18 (18) 18 (18)
3vqf 85 1.20 43 α/β C121 0.70 (0.70) 0.68 (0.77) 27 (27) 22 (22)
3vwc 146 1.50 50 β C121 0.76 (0.76) 0.65 (0.80) 22 (22) 12 (22)
3zdb 246 1.47 59 α/β P21212 0.79 (0.79) 0.76 (0.81) 34 (34) 34 (34)
4a3z 136 1.55 45 β P43212 0.80 (0.80) 0.79 (0.80) 98 (98) 22 (98)
4dcd 184 1.69 43 β I222 0.78 (0.85) 0.71 (0.85) 44 (44) 44 (44)
4is7 140 2.75 70 α P6522 0.80 (0.80) 0.78 (0.81) 59 (59) 18 (59)
4kr1 219 2.50 52 α/β P6322 0.80 (0.80) 0.73 (0.82) 40 (40) 40 (54)
4l8g 157 1.52 38 α/β P636 0.75 (0.81) 0.75 (0.81) 25 (37) 25 (37)
4lvp 124 2.32 55 α P6422 0.77 (0.88) 0.69 (0.82) 100 (100) 100 (100)
4m6t 177 2.50 74 α+β H32 0.70 (0.81) 0.74 (0.74) 100 (100) 100 (100)
4mdn 94 1.91 68 β P41212 0.64 (0.64) 0.65 (0.64) 67 (67) 67 (67)
4mjf 225 1.99 50 α C121 0.79 (0.86) 0.74 (0.88) 52 (97) 52 (97)
4nbr 268 1.35 41 α/β I222 0.88 (0.88) 0.84 (0.91) 22 (22) 22 (22)
4oq4 186 1.49 59 α/β P3121 0.80 (0.80) 0.79 (0.84) 22 (22) 22 (24)
Average 183 1.88 60     0.77 (0.82) 0.76 (0.81) 54 (59) 49 (58)