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. 2018 Jun 26;2018:5083234. doi: 10.1155/2018/5083234

(b) Diagnostic testing performed on the primary CNS mature B-cell lymphomas presented as an amyloidomas published in literature

Reference Imaging Histopathology Light chain restriction Bone marrow Systemic amyloidosis Lab tests Molecular testing
(1) Lehman et al. [1] MRI- isointense on T1 and hyperintense on T2 Intracerebral and vascular amyloid deposition, CD 20+ B cells and plasmacytoid cell infiltrates, CD138+ plasma cells Kappa Normal NR SPEP and UPEP- normal,
CBC- normal
ND

(2) Pace et al. [2] MRI- isointense on T1, hypointense on T2 Intracerebral and vascular amyloid deposition, CD 20+ B cells and plasmacytoid cell infiltrates, CD138+ plasma cells Kappa Normal Ruled out by serum amyloid P component scan SPEP- normal, normal serum free kappa, free lambda and kappa: lambda ratio ND

(3) Tu et al. [3] NR Amyloid deposition, CD20 + B cell infiltrates Kappa NR NR NR Trisomy 3 positive, Negative for MALT1 and IgH translocation

(4) Tu et al. [3] NR Amyloid deposition, cyclin D1-, CD20 + B-cell infiltrates Kappa NR NR NR Trisomy 3 positive, Negative for MALT1 and IgH translocation

(5) Our case MRI-T2 hyperintense Intraparenchymal and perivascular amyloid deposition (AL subtype). CD20+, CD3-, CD5-, BCL1-, CD23- plasmacytoid lymphocytes and CD138+ plasma cells Lambda Normal Ruled out by abdominal fat biopsy Normal serum free kappa, free lambda and kappa: lambda ratio MYD88 L265P mutation analysis was negative

NR: not reported; ND: not done.