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. Author manuscript; available in PMC: 2018 Jul 10.
Published in final edited form as: IEEE Trans Vis Comput Graph. 2017 Aug 29;24(1):522–531. doi: 10.1109/TVCG.2017.2745978

Fig. 3.

Fig. 3

Hi-C methodology: as the DNA (1) is organized non-arbitrarily in the cell nucleus (2), certain parts (highlighted in orange and blue) are frequently in close contact (3). These contacts are quantified over a set of several hundred million cells(4), leading to interaction matrix of up to 3 by 3 million cells (5). Dark colors indicate more frequent contacts occurrences of two loci.