Table 1.
Long non-coding RNA implicated in Rheumatoid arthritis.
| LncRNAs | Sample | Chromosome locus (hg38) | Expression | Related proteins | References |
|---|---|---|---|---|---|
| HOTAIR | PBMC, exosome | Chr12: 53962308–53974956 | Up-regulated | MMP2, MMP3 | (62) |
| ENST00000483588 | RAFLSs | Chr17: 16428987–16470648 | Up-regulated | ATAD3A,NDUFA4L2 | (63) |
| ENST00000438399 | RAFLSs | Chr10: 29698475–29713107 | Down-regulated | PTPRQ,PTHLH | (63) |
| uc004afb.1 | RAFLSs | Chr: 41007011–41074625 | Down-regulated | TNFRSF11B | (63) |
| ENST00000412143 | RAFLSs | Chr: 31173735–31177899 | Down-regulated | (63) | |
| ENST00000452247 | RAFLSs | Chr10: 52296848–52314128 | Down-regulated | ZNF154,WISP3 | (63) |
| LOC100652951 | T cells | Up-regulated | (64) | ||
| LOC100506036 | T cells | Chr2: 96811821–96815889 | Up-regulated | SMPD1, NFAT1 | (64) |
| ENST00000445339 | PBMC | Chr1: 230002730–230007162 | Down-regulated | (65) | |
| ENST00000506982 | PBMC | Chr4: 143953634–144126359 | UP-regulated | (65) | |
| MALAT1 | RAFLSs | Chr11: 65497679–65504494 | UP-regulated | Caspase3, Caspas9 | (66) |
| RNA143598 | Serum | UP-regulated | (25) | ||
| RNA143596 | Serum | UP-regulated | (25) | ||
| HIX0032090 | Serum | UP-regulated | (25) | ||
| GHCgamma1 | Serum | UP-regulated | (25) | ||
| XLOC_002730 | Serum | UP-regulated | (25) | ||
| ZFAS1 | Synovial, RAFLSs | Chr20: 49278177–49289260 | UP-regulated | miR27a | (67) |
| lincRNA-p21 | Whole blood | Chr17: 29057473–29078961 | Down-regulated | REAL,NF-KB | (68) |
| H19 | synovial tissue | Chr11: 1995682–2001470 | UP-regulated | (69) | |
| NR_024118 | Mouse model | SOCS3,MMP1,MMP3 | (70) | ||
| C5T1 | PBMC | Chr9: 120942252–120952831 | UP-regulated | C5 | (71) |
| GAS5 | CD4 T cells, B cells | Chr1: 161035166–161038537 | Down-regulated | mTOR,GR | (72) |
| ENST00000456270 | PBMC | Chr7:117604790–117647415 | Up-regulated | (73) | |
| NR_002838 | PBMC | Chr18:41480270–41520597 | Up-regulated | (73) | |
| NR_026812 | PBMC | Chr21:35037935–35039426 | Down-regulated | (73) | |
| uc001zwf.1 | PBMC | Chr15:48426827–48428972 | Down-regulated | (73) |