Table. Sampling time, serotype, and sources of serum/plasma panels in study of use of urea wash ELISA to distinguish Zika and dengue virus infections*.
Panel sample collection times | Category | Sampling time after symptom onset, mean (range) | No. patients | Source (no. patients) and year(s) of sample collection | Shown in |
---|---|---|---|---|---|
Single time point | |||||
pDENV-1 | Convalescent to postconvalescent | 138 (19−263) d | 16 | Taiwan (4), 2001–2002; Hawaii, USA (12), 2015 | Figure 1 |
pZIKV | Convalescent | 17 (14−24) d | 20 | Nicaragua, 2016 | Figure 1 |
sDENV | Convalescent | 14 (8−35) d | 24 | Taiwan, 2001–2002 | Figure 1 |
DENV-ZIKV | Convalescent | 16 (14−19) d | 20 | Nicaragua, 2016 | Figure 1 |
Probable DENV-ZIKV | Convalescent | 10 (6−14) d | 19 | Brazil, 2015–2016 | Figure 1 |
sDENV | Postconvalescent | 3.2 (3−4) mo | 6 | Taiwan (2), 2006–2009; Nicaragua (4), 2006–2008 | Figure 2 |
sDENV | Postconvalescent | 12 (12−12) mo | 18 | Nicaragua, 2006–2008 | Figure 2 |
sDENV | Postconvalescent | 19.7 (18−24) mo | 14 | Taiwan (10), 2006–2009; Nicaragua (4), 2006–8 | Figure 2 |
sDENV |
Postconvalescent |
71 (67−72) mo |
5 |
Taiwan, 2006–2009 |
Figure 2 |
Sequential time points | |||||
sDENV | Postconvalescent | 10 (3−18) mo | 3 | Nicaragua, 2006–2008 | Figure 2 |
*DENV-ZIKV, ZIKV infection with previous dengue; pDENV-1, primary dengue virus 1 infection; pZIKV, primary Zika virus infection; sDENV, secondary dengue virus infection. †3–4 samples/patient.