. 2018 Jul 6;6(1):e000524. doi: 10.1136/bmjdrc-2018-000524

Table 3.

Discrimination and reclassification of the original GDRS and the clinical GDRS in the EPIC-Potsdam and GNHIES98 cohort

Performance measure	EPIC-Potsdam	GNHIES98 cohort
C-index_GDRS (95% CI)	0.83 (0.81 to 0.84)	0.87 (0.84 to 0.90)*
C-index_{Clinical GDRS} (95% CI)	0.87 (0.81 to 0.92)	0.91 (0.88 to 0.94)*
NRI (95% CI)	0.26 (0.21 to 0.30)	–
NRI_non-cases (95% CI)	0.02 (0.01 to 0.02)	–
NRI_cases (95% CI)	0.24 (0.19 to 0.28)	–

*In GNHIES98 cohort, ROC-AUC was calculated based on logistic regression.

EPIC, European Prospective Investigation into Cancer and Nutrition; GDRS, German Diabetes Risk Score; NRI, net reclassification improvement; ROC-AUC, area under the receiver-operating characteristic curve.