Table 2.
DMT1 location and intensity scoring.
| Species | Location | IC Intensitya | IC Intensity | |
|---|---|---|---|---|
| Controls | Mouse | CNS Neurons | +++ | |
| Basal area gut epithelium | ++ | |||
| Nematodes | Filarial Parasites | O. volvulus | B. malayi | |
| Cuticle | – | – | ||
| Hypodermis | + to ++ | + to ++ | ||
| Body wall muscle | – to + | – | ||
| Intestinal wall | + | ++ | ||
| Uterine wall | ++ | + to ++ | ||
| Uterine oocytes | – | – | ||
| Uterine morulae | ++ | + to +++ | ||
| Uterine microfilariae | – to +++ | – to + | ||
| Emerged microfilariae | + to +++ | |||
| Intra-male spermatozoa | – | – | ||
a
IC Intensity level: Based on the overall intensity observed in all positive locations compared to tissue control in the same section. Range: no staining (−); weak staining (+); moderate staining (++); strong staining (+++).