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. 2018 Jul 4;13:3867–3881. doi: 10.2147/IJN.S161423

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© 2018 Zhou et al. This work is published and licensed by Dove Medical Press Limited

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Cell morphology on nanoscaled and microscaled topographical surface. hASCs exhibited elongated cell shape on microgrooved surface (G) and spread cell shape on smooth membrane (S) when observed under phase contrast microscope (A) and fluorescence microscope with actin-staining (B) on day 3 postseeding (40× and 100×, bar =150 µm). Similarly, hASCs also exhibited elongated cell shape on parallel electrospun nanofibers (parallel) and spread cell shape on random electrospun nanofibers (unparallel) when observed under fluorescence microscope with actin staining (C) at various time points (100×, bar =100 µm).

Abbreviation: hASCs, human adipose-derived stem cells.