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. 2018 Jul 4;13:3867–3881. doi: 10.2147/IJN.S161423

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© 2018 Zhou et al. This work is published and licensed by Dove Medical Press Limited

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qPCR analysis of the effect of nanoscaled aligned topography on hASC differentiations toward the lineages of osteogenic (A and B), chondrogenic (C and D), adipogenic (E and F), and myogenic (G and H) on day 3 (A, C, E, G) and on day 7 (B, D, F, H). *p<0.05; **p<0.01.

Abbreviations: ALPL, alkaline phosphatase, liver/bone/kidney; AP-2α, adipocyte protein 2α; CEB/Pα, CCAAT/enhancer binding protein (C/EBP) α; COL2, type II collagen; hASCs, human adipose-derived stem cells; MAP2, microtubule-associated protein 2; MyoD, myoblast determination protein; OCN, osteocalcin; PPARγ, peroxisome proliferator-activated receptor-γ; qPCR, quantitative PCR; Runx2, Runt-related transcription factor 2; Sox9, SRY (sex determining region Y)-box 9.