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. 2018 Jul 5;12:2051–2069. doi: 10.2147/DDDT.S161940

Table S2.

Change in the position of chemical shifts of EDR and NEF in 1H NMR spectroscopy

EDR (chemical shift) NEF (chemical shift) Change
11.543 11.459 0.084
7.755 7.706 0.049
7.417 7.422 −0.005
7.195 7.193 0.002
5.381 5.356 0.025
2.136 2.107 0.029

Abbreviations: EDR, edaravone; NEF, novel EDR formulation; NMR, nuclear magnetic resonance.