Skip to main content
. Author manuscript; available in PMC: 2018 Jul 10.
Published in final edited form as: Science. 2017 Sep 14;358(6360):234–238. doi: 10.1126/science.aao3130

Fig. 2. Mutational burden in DNA repair–deficient human colonic stem cells.

Fig. 2

(A) Number of mutations accumulated in the absence of the indicated DNA repair proteins per day. Base substitutions subdivided by mutation type and INDELs are shown. (B) Size distribution of the observed INDELs per genotype. A negative value indicates deletions and a positive value indicates insertions. (C) Number of INDELs located in simple repeats per genotype. Indicated are the number of repetitive subunits surrounding an inserted or deleted subunit. A value of 0 indicates that the INDEL is not located within a simple repeat.