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. Author manuscript; available in PMC: 2018 Oct 11.
Published in final edited form as: Nature. 2018 Apr 11;556(7701):332–338. doi: 10.1038/s41586-018-0023-4

Extended Data Figure 4. Cytokine levels in 9-month-old animals.

Extended Data Figure 4

a, Cytokine measurements in brain homogenates of 9-month-old wildtype (n=8,8,7 animals) and APP23 (n=14,10,10 animals) mice treated i.p. with 1x or 4xLPS at 3 months of age. b, Cytokine measurements in the serum of 9-month-old wildtype (WT; n=14,9,13 animals) and APP23 (APP; n=18,12,14 animals) mice after i.p. stimulation with 1x or 4xLPS at 3 months of age. c, Cytokine measurements in the serum of wildtype animals stimulated i.p. with 1x or 4xLPS at 3 months of age and re-stimulated with an additional LPS injection (500 µg/kg) at 9 months of age (n=10,7,10 animals). Data are means±s.e.m. */** P <0.05/0.01 for two-way ANOVA with Tukey correction. In (b) a significant main effect for genotype is indicated by bars spanning all conditions of the same genotype.