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. Author manuscript; available in PMC: 2019 Feb 1.
Published in final edited form as: Clin Cancer Res. 2018 Feb 2;24(15):3681–3691. doi: 10.1158/1078-0432.CCR-17-2259

Figure 4. The clinical significance of nuclear expression level of BQ323636.1.

Figure 4

A) Representative images of BQ323636.1 IHC staining in primary breast cancer samples in TMA. Mann-Whitney test demonstrating BQ323636.1 nuclear score was associated with B) Tamoxifen resistance C) Metastasis and D) Recurrence *** p<0.001, ** p<0.01, * p<0.05. Nuclear BQ323636.1 scores were dichotomized at the median value and Chi square test performed for association with B) Tamoxifen resistance, C) Metastasis and D) Recurrence (Chi square test p<0.0001).

Kaplan-Meier estimate shows the patients with high nuclear BQ323636.1 expression were associated with poorer E) overall survival outcome (p < 0.001) and F) disease specific survival outcome (p<0.001) (Log-rank test). Nuclear BQ323636.1 scores were dichotomized at the median value.