Table 1. Characteristics of patients with Crohn disease and patients with ulcerative colitis.
| Characteristics | Crohn disease (n = 13925) | Ulcerative colitis (n = 29356) | P valuea |
|---|---|---|---|
| Age, years, mean ± SD | 34.0 ± 13.8 | 45.7 ± 14.4 | < .0001 |
| Male sex | 8846 (63.53%) | 17067 (58.14%) | < .0001 |
| Anti-inflammatory drugs | |||
| Corticosteroids | 6701 (48.12%) | 16002 (54.51%) | < .0001 |
| Mesalazine | 9576 (68.77%) | 20641 (70.31%) | 0.0011 |
| Balsalazide | 160 (1.15%) | 3162 (10.77%) | < .0001 |
| Immunosuppressants | |||
| Methotrexate | 178 (1.28%) | 186 (0.63%) | < .0001 |
| Azathioprine | 6462 (46.41%) | 3758 (12.8%) | < .0001 |
| Sulfasalazine | 414 (2.97%) | 2223 (7.57%) | < .0001 |
| 6-mercaptopurine | 593 (4.26%) | 173 (0.59%) | < .0001 |
| TNF-alpha inhibitors | |||
| Adalimumab | 865 (6.21%) | 322 (1.1%) | < .0001 |
| Infliximab | 2056 (14.76%) | 971 (3.31%) | < .0001 |
| Golimumab | 4 (0.03%) | 6 (0.02%) | 0.7361b |
| Etanercept | 5 (0.04%) | 14 (0.05%) | 0.8065b |
SD, standard deviation; TNF, tumor necrosis factor.
a P values were calculated using the chi-square test.
b P values were calculated using the Fisher exact test.