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. 2018 Jul 10;15(7):e1002602. doi: 10.1371/journal.pmed.1002602

Table 5. Summary of cumulative incidence of cases avoided and cumulative costs avoided in England for each scenario relative to baseline for PM2.5 and NO2, by period.

Scenario Parameter PM2.5 NO2
2017 (95% CI) 2017–2025 (95% CI) 2017–2035 (95% CI) 2017 (95% CI) 2017–2025 (95% CI) 2017–2035 (95% CI)
Baseline Cumulative incidence of cases 644,873
(643,114 to 646,632)
6,119,754
(6,114,646 to 6,124,862)
13,654,072
(13,645,973 to 13,662,171)
661,566
(659,721 to 663,411)
6,215,963
(6,210,268 to 6,221,658)
13,855,589
(13,847,049 to 13,864,129)
1-μg/m3 reduction in PM2.5 and NO2 Cumulative incidence of cases 636,526
(634,767 to 638,285)
6,033,265
(6,028,157 to 6,038,373)
13,465,656
(13,457,557 to 13,473,755)
659,896
(658,051 to 661,741)
6,198,788
(6,193,093 to 6,204,483)
13,822,000
(13,813,460 to 13,830,540)
Cumulative incidence of cases avoided (relative to baseline) 8,345
(6,191 to 10,499)
86,483
(80,227 to 92,739)
188,415
(178,496 to 198,334)
1,669
(−880 to 4,218)
17,173
(9,303 to 19,866)
33,589
(21,789 to 36,435)
Total cost avoided relative to baseline (millions of British pounds)* 11.6
(3.4 to 19.8)
408.3
(380.8 to 435.8)
1,424.2
(1,378.3 to 1,470.1)
4.09
(−12.24 to 20.42)
108.71
(53.73 to 163.69)
353.33
(260.16 to 446.5)
Primary care cost avoided 1.59
(−1 to 4.18)
50.27
(41.64 to 58.9)
167.16
(152.8 to 181.52)
0.69
(−2.01 to 3.39)
19.89
(10.89 to 28.89)
65.63
(50.61 to 80.65)
Secondary care cost avoided 5.56
(−0.31 to 11.42)
196.62
(177.09 to 216.15)
683.71
(651 to 716.42)
0.97
(−2.65 to 4.59)
27.94
(15.91 to 39.97)
92.1
(72.08 to 112.12)
Medication cost avoided 2.91
(−0.38 to 6.2)
102.95
(91.97 to 113.93)1
362.59
(344.2 to 380.98)
0.56
(−1.53 to 2.65)
16.07
(9.12 to 23.02)
53.05
(41.47 to 64.63)
Social care cost avoided 1.51
(−2.51 to 5.53)
58.48
(45.1 to 71.86)
210.73
(188.45 to 233.01)
1.87
(−13.68 to 17.42)
44.81
(−7.62 to 97.24)
142.55
(53.55 to 231.55)
EU limit values met Cumulative incidence of cases Not applicable 652,106
(650,261 to 653,951)
6,119,176
(6,113,481 to 6,124,871)
13,630,127
(13,621,587 to 13,638,667)
Cumulative incidence of cases avoided (relative to baseline) 9,458
(6,909 to 12,007)
96,786
(88,916 to 104,656)
225,465
(213,665 to 237,265)
Total cost avoided relative to baseline (millions of British pounds)* Not applicable 12.92
(−3.41 to 29.25)
442.81
(387.84 to 497.78)
1,692.87
(1,599.75 to 1,785.99)
Primary care cost avoided 2.34
(−0.36 to 5.04)
83.19
(74.2 to 92.18)
324.1
(309.11 to 339.09)
Secondary care cost avoided 3.25
(−0.37 to 6.87)
116.9
(104.88 to 128.92)
456.06
(436.08 to 476.04)
Medication cost avoided 2.02
(−0.07 to 4.11)
71.7
(64.75 to 78.65)
280.19
(268.63 to 291.75)
Social care cost avoided 5.31
(−10.24 to 20.86)
171.02
(118.6 to 223.44)
632.52
(543.56 to 721.48)

Scaling to the population of England may lead to rounding discrepancies between cases and costs avoided.

*All costs are in millions of British pounds and are for the total population of England.