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. 2018 Jul 6;11:3919–3929. doi: 10.2147/OTT.S166149

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© 2018 Yu et al. This work is published and licensed by Dove Medical Press Limited

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The changes of key enzymes or genes in the reprogrammed metabolic pathways of SCLCC revealed by targeted proteomics and qPCR analysis.

Notes: (A–F) targeted proteomics; (G) qPCR analysis. Data were mean±SD, n=6 for targeted proteomics and n=3 for qPCR analysis. *p<0.05 and **p<0.01 according to Student’s t-test.

Abbreviations: APRT, adenine phosphoribosyltransferase; CPS1, carbamoyl phosphate synthase 1; CPT1A, carnitine palmitoyltransferase 1A; CPT2, carnitine palmitoyltransferase 2; HBEC, human bronchial epithelial cells; HPRT, hypoxanthine-guanine phosphoribosyltransferase; qPCR, quantitative polymerase chain reaction; SCLCC, small cell lung cancer cells; XDH, xanthine dehydrogenase.