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. 2018 Jun 6;20(12):3666–3669. doi: 10.1021/acs.orglett.8b01459

Table 1. Optimization Studies Using 1a as Substrate.

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entrya C4F9I (equiv) solvent (mL) yield (%)b E/Z (ratio)c
1 1.5 MeCN (2) 63 4:1
2 2.0 MeCN (2) 67 5:1
3 5.0 MeCN (2) 69 9:1
4 10.0 MeCN (2) 69 12:1
5 5.0 MeCN (1) 66 8:1
a

Reactions were conducted with 1a (0.3 mmol).

b

Yields provided represent isolated yields.

c

Selectivity was determined by 1H NMR spectroscopy.