Table 2.
Study quality assessment by QUADAS-2 criteria
| Risk of bias
|
Applicability concerns
|
||||||
|---|---|---|---|---|---|---|---|
| References | Patient selection | Index test | Reference standard | Flow and timing | Patient selection | Index test | Reference standard |
| Warkentin* 2013 [19] | Low | Unclear | Low | Low | Low | High | High |
| Cuker 2013 [20] | High | Unclear | High | Low | Low | Low | High |
| Galea 2013 [21] | Low | Unclear | Unclear | Low | Low | Low | High |
| McFarland 2012 [22] | High | Unclear | High | High | Low | High | High |
| Van Hoecke 2012 [13] | Low | Unclear | High | Low | Low | Low | High |
| Morel-Kopp 2010 [23] | Low | Low | High | High | Low | Low | High |
| Pouplard 2010 [24] | High | Unclear | Low | Low | Low | Low | High |
| Bakchoul 2009 [25] | Low | Unclear | Unclear | Low | Low | High | High |
| Warkentin 2008 [15] | Low | Unclear | High | High | Low | High | High |
*
Determined from data reported in original article, the PROTECT trial, and discussions with Dr. Theodore Warkentin.