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. Author manuscript; available in PMC: 2018 Jul 10.
Published in final edited form as: J Thromb Haemost. 2017 May 11;15(6):1203–1212. doi: 10.1111/jth.13692

Table 4.

Operating characteristics of IgG-specific and polyspecific ELISA

Sensitivity (95% CI) Specificity (95% CI) PPV (95% CI) NPV (95% CI) PLR* NLR*
IgG-specific 0.97 (0.97–0.99) 0.87 (0.85–0.88) 0.56 (0.52–0.61) 0.99 (0.99–1.00) 7.38 0.03
Polyspecific 0.97 (0.97–0.99) 0.82 (0.80–0.84) 0.32 (0.28–0.35) 0.99 (0.99–1.00) 5.07 0.03

CI, confidence interval; PPV, positive predictive value; NPV, negative predictive value; PLR, positive likelihood ratio; NLR, negative likelihood ratio.

*

Calculated as point estimates from sensitivity and specificity.