Table 4.
Operating characteristics of IgG-specific and polyspecific ELISA
Sensitivity (95% CI) | Specificity (95% CI) | PPV (95% CI) | NPV (95% CI) | PLR* | NLR* | |
---|---|---|---|---|---|---|
IgG-specific | 0.97 (0.97–0.99) | 0.87 (0.85–0.88) | 0.56 (0.52–0.61) | 0.99 (0.99–1.00) | 7.38 | 0.03 |
Polyspecific | 0.97 (0.97–0.99) | 0.82 (0.80–0.84) | 0.32 (0.28–0.35) | 0.99 (0.99–1.00) | 5.07 | 0.03 |
CI, confidence interval; PPV, positive predictive value; NPV, negative predictive value; PLR, positive likelihood ratio; NLR, negative likelihood ratio.
Calculated as point estimates from sensitivity and specificity.