Official websites use .gov
A
.gov website belongs to an official
government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you've safely
connected to the .gov website. Share sensitive
information only on official, secure websites.
R9C PLN human engineered cardiac tissues (hECTs) have a blunted β-agonist response. hECTs derived from wild-type or inserted R9C hiPSC-CMs were tested during stimulation at 0.5Hz for (A) developed force and (B) time to relaxation (50%) before and after day 35 of differentiation. (C) Spontaneous beat rate and (D) time to relaxation (50%) were determined on wild-type and R9C hECTs after day 35 before and after treatment with 500nM isoproterenol.
