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. Author manuscript; available in PMC: 2019 Jun 1.
Published in final edited form as: J Mol Cell Cardiol. 2018 May 9;119:147–154. doi: 10.1016/j.yjmcc.2018.05.007

Figure 6.

Figure 6

Transcriptional response to R9C PLN results in perturbation of miRNAs linked to cardiac metabolism and fibrosis. (A) Differentially expressed miRNAs in R9C PLN hiPSC-CMs compared to the isogenic control. miRNAs expressed at least 2-fold higher or lower in R9CPLN hiPSC-CMs are shown in red. (B) Differentially expressed miRNAs involved in cardiac metabolism or fibrosis (expressed at least 2-fold higher in the PLN mutant). miRNAs in red or blue are upregulated or downregulated, respectively. (C) Quantitative PCR analysis confirming perturbed expression of miRNAs shown in (B).