Schematic presentation of cyclooxygenase and lipoxygenase pathway
PGH2: prostaglandin H2; PGF2: prostaglandin F2; PGD2: prostaglandin D2; PGE2: prostaglandin E2; PGI: prostacyclin; TXA2: thromboxane A2; PHJ2: prostaglandin J2; PGF2α: prostaglandin F2α; MMP9: matrix metalloproteinase 9; VEGF: vascular endothelial growth factor; TP: thromboxane receptor; EP1, 2, 3, and 4: prostaglandin E receptors; HUVEC: human umbilical vein endothelial cell; PPAR: peroxisome proliferator-activated receptor; PTEN: phosphatase and tensin homolog