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. Author manuscript; available in PMC: 2019 Jul 15.
Published in final edited form as: J Immunol. 2018 Jun 8;201(2):393–405. doi: 10.4049/jimmunol.1701588

Figure 5. Immune complex deposition in the kidney is interferon-independent.

Figure 5

10 week- old NZM2328 and INZM mice treated with R848 or DMSO until moribund and were analyzed for immune complex deposition. A. Representative immunofluorescence microscopy of glomeruli (outlined by white dashed line). Texas Red- IgG, Green- C3, Blue- DAPI. (B–C). Quantification of immune complex staining/area was completed. Littermate DMSO controls were harvested when littermates were ill. B. Quantification of IgG/area. C. Quantification of C3/area. Each dot represents the average fluorescence of 8 glomeruli from a single mouse.