WT mice were challenged sublingually with PBS (sham) or C. albicans (OPC). (A) Tongue homogenates were prepared 2 days post-infection (p.i.), and total mRNA was subjected to quantitative real-time polymerase chain reaction (qPCR) normalized to Gapdh. Graphs depict relative expression of indicated genes as mean + SEM, and normalized to sham. Data are compiled from 3–5 mice per group from two independent experiments. (B) Relative mRNA expression of indicated genes in the tongue at 0, 12, and 24 h p.i. Data are compiled from 3–5 WT mice per group from a single experiment. Data were analyzed by Student’s t test or one-way ANOVA. *P < 0.05, **P < 0.01, and ***P < 0.001.