Table 4.

Specific enzyme activities in crude extracts of trophozoites of the MET/NTZ resistant strain C4 and of the wild-type (WT) WBC6. Pyruvate-oxido-reductase and ornithine-carbamyl-transferase activities were determined as described in Materials and Methods. Mean values ± SE are given for three independent extracts. Values marked by asterisks are significantly different to the control (paired t-test, two-sided; *, p < 0.01).

Activity	Unit	WT	C4
Pyruvate-oxido-reductase	ΔmA590/min/mg protein	34.3 ± 6.0	46.6 ± 6.6
Ornithine-carbamyl-transferase	nkat/mg protein	94.5 ± 0.7	37.1 ± 6.5*