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Efficacy of Cry5B SCL against A. caninum infections in dogs. Two dogs were pre-treated with famotidine and dexmedetomidine, treated with Cry5B, and post-treated with atipamezole. The dose of Cry5B was 40 mg/kg on day 42 and day 44 p. i. Shown are (A) average hookworm burdens based on capsule endoscopy and (B) average fecal egg counts (eggs per gram of feces or EPG) five days after the second treatment.
