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. Author manuscript; available in PMC: 2019 Apr 1.
Published in final edited form as: Curr HIV/AIDS Rep. 2018 Apr;15(2):172–181. doi: 10.1007/s11904-018-0379-y

Figure 1. Hepatitis B Virus Life Cycle.

Figure 1

Figure 1 depicts the HBV lifecycle. Yellow arrows highlight cccDNA and the production of the core protein, demonstrating that the production of core protein occurs independent of HBV viral replication and as a direct result of the presence of the transcriptionally active reservoir of cccDNA

Modified from: Ait-goughoulte Malika, Lucifora J, Zoulim F, Durantel D. Innate Antiviral Immune Responses to Hepatitis B Virus. Viruses. 2010;2(7):1394-1410. doi:10.3390/v2071394. Modified with permission from Creative Commons Attribution License (CC BY 3.0) https://creativecommons.org/licenses/by-nc-sa/3.0/legalcode.